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Michał Glanowski, MSc, Eng.

PhD Student
Phone: +48 12 6395 156
Room: 236
E-mail: michal.glanowski@ikifp.edu.pl

Research Topics:

  • Study of the reaction mechanism of 3-ketosteroid D1-dehydrogenases from Rhodococcus  erythropolis and Sterolibacterium denitrificans
  • Quantum-chemical modeling of reaction paths
  • homologous modeling of the structure of enzymes based on the known amino acid sequence and known 3D structures of similar enzymes
  • Quantum-mechanical modeling of the enzymatic reaction based on the cluster model of the active center

Methods:

  • Molecular dynamics methods
  • DFT modeling
  • QM:MM 
  • QM:MM:MD modeling of reaction pathways and kinetic isotope effect