Research Infrastructure and Equipment

 

Our laboratory is equipped with advanced infrastructure supporting research in biotechnology, protein engineering, and analytical chemistry. The available instrumentation enables both fundamental and applied studies, from microbial cultivation to detailed molecular analysis.

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Biochemical and Microbiological Equipment

The laboratory provides facilities for microbial cultivation, bioprocess development, and downstream processing at multiple scales.

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• Parallel bioreactor systems (2 × 2 × 5 L working vessels)

• BioLector XT microbioreactor system for high-throughput screening

• Laboratory-scale bioreactors (30 L and 200 L)

• Incubators and shaker incubators (Binder, Thermo Scientific MaxQ™ 6000, New Brunswick Excella E24R, LabCampanion ISS-4075R)

• Continuous-flow and preparative centrifuges

• Cell disruption systems (Sonics Vibra-Cell VCX500, EmulsiFlex-C3 homogenizer)

• Autoclave (Tuttnauer D-line 5075 ELV)

• Facilities for downstream processing

 

Protein Purification Facilities

Dedicated infrastructure supports protein isolation and purification under both aerobic and anaerobic conditions.

• Cold room laboratory for biochemical studies

• Anaerobic glove box for oxygen-sensitive protein work

• FPLC systems (AKTApurifier UPC 10, NGC Quest 10 Plus, AKTA Start)

• Ultracentrifuges (Beckman) and high-speed centrifuge (Hermle Z36HK)

• Vacuum concentrator and freeze dryer (Labconco)

• Deep freezers (-70 °C) and ultra-low temperature freezers (-86 °C)

 

Analytical Equipment

A wide range of analytical techniques is available for qualitative and quantitative characterization of biomolecules and chemical compounds.

• LC-MS and LC-MS/MS systems (Agilent platforms)

• Gas chromatograph (Varian CP-3800, TCD and FID)

• Capillary electrophoresis system (Hewlett-Packard)

• Gel electrophoresis systems for proteins and DNA

• PCR and Real-Time PCR systems (CFX Connect)

• Solid phase extraction systems

• Optical and analytical instruments (microscopy, CHNS analysis)

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Biophysical Equipment

Biophysical instrumentation enables detailed studies of molecular interactions, stability, and thermodynamics.

• UV-Vis spectrophotometers with temperature control

• Microplate spectrophotometer (BioTek Epoch)

• Isothermal titration calorimeter (TAM III, Thermometric)

• Real-Time PCR detection system

 

Computational Facilities

Computational resources support molecular modelling, simulation, and data analysis.

• Access to high-performance computing infrastructure (CYFRONET / PLGRID)

• Software for quantum chemistry, molecular dynamics, and molecular docking

• Tools for reaction kinetics and equilibrium simulations (KinTek Explorer, Python-based workflows)