The tungsten enzyme turns out to be a new hydrogenase!
It is my pleasure to share with you our discovery in its fullness. We submitted a preprint of our paper reporting that W-containing Aldehyde Oxidoreductase (AOR) from mesophilic bacterium A. aromaticum exhibits activity of hydrogenase. This enables H2-dependent reduction of carboxylic acids to valuables compounds (e.g. vanillin) or sustainable recycling of NADH. The specific activity of H2-dependent NAD+ reduction exceeds any previously observed reactivities of Mo- or W-enzyme with hydrogen.
We already submitted a European Patent Application to secure the IP rights to this exciting discovery. In the meantime, you can have a look at our scientific results and share your thoughts/ideas with us.