First part of the FunBioMed project employs production of bacterial polymers in a controlled manner. PHA polymers will be functionalised using a variety of enzymes with different drugs (such as antibiotics, steroids and nonsteroidal anti-inflammatory drugs). Next we will formulate materials for specific applications and describe their physical properties on micro and macro scales.

The final stage of the project envisages testing of the chosen functionalised PHAs in vivo. We will proceed with an animal model in order to assess the effectiveness of novel biomaterials in wound healing.

Once we will establish the production process and describe phiscal properties of the novel materials, we will start biological tests. The novel functionalised materials will be characterized in vitro for their biocompatibility with chosen cell lines appropriate for their future applications. In parallel we will conduct test in order to descibe antibacterial properties of the novel functionalised PHAs.

PROJECT LIDER "Novel functionalised biopolymers for medical applications" is sponsored by the Polish National Centre for Research and Developement