FunBioMed - "Novel functionalised biopolymers for medical applications"
Maciej Guzik, PhD
Karolina Stepien, MSc
Daria Solarz, MSc
Szymon Skibinski, MSc, Eng.
Mariusz Sołtysik, PhD
Scientist with PhD
Tomasz Witko, PhD
Martyna Seta, MSc
Katarzyna Harazna, MSc, Eng
Ewelina Cichon, MSc, Eng.
Production of novel functionalised polymers and characterization of their material properties
First part of the FunBioMed project employs production of bacterial polymers in a controlled manner. PHA polymers will be functionalised using a variety of enzymes with different drugs (such as antibiotics, steroids and nonsteroidal anti-inflammatory drugs). Next we will formulate materials for specific applications and describe their physical properties on micro and macro scales.
Testing materials for their applications in medicine
The final stage of the project envisages testing of the chosen functionalised PHAs in vivo. We will proceed with an animal model in order to assess the effectiveness of novel biomaterials in wound healing.
Biological properties characterization of novel materials
Once we will establish the production process and describe phiscal properties of the novel materials, we will start biological tests. The novel functionalised materials will be characterized in vitro for their biocompatibility with chosen cell lines appropriate for their future applications. In parallel we will conduct test in order to descibe antibacterial properties of the novel functionalised PHAs.
PROJECT LIDER "Novel functionalised biopolymers for medical applications" is sponsored by the Polish National Centre for Research and Developement